Management Team

Management Team

Mesoblast has a highly experienced management team made up of individuals who have held senior positions in international pharmaceutical and biotechnology companies. This team is responsible for the strategic direction, operations and success of our company.

 

Silviu Itescu, MBBS, FRACP

Chief Executive Officer & Managing Director

Dr Itescu has served on Mesoblast's Board of Directors since the Company's founding in 2004, was Executive Director from 2007, and became Chief Executive Officer and Managing Director in 2011. Prior to founding Mesoblast in 2004, he established an international reputation as a physician scientist in the fields of stem cell biology, autoimmune diseases, organ transplantation, and heart failure. Dr Itescu has been a faculty member of Columbia University in New York, and the University of Melbourne and Monash University in Australia. In 2013, Dr Itescu received the inaugural Key Innovator Award from the Vatican’s Pontifical Council for Culture for his leadership in translational science and clinical medicine in relation to adult stem cell therapy. In 2011, he was named BioSpectrum Asia Person of the Year. He has consulted for various international pharmaceutical companies, has been an adviser to biotechnology and health care investor groups, and has served on the Board of Directors of several publicly listed life sciences companies.

Josh Muntner, BFA, MBA

Chief Financial Officer

Mr Muntner has accrued 20 years’ experience in healthcare investment banking and corporate finance, and has been involved in a wide range of healthcare-related transactions with approximately $11 billion in value. Most recently, he led corporate development and financial transactions at Nasdaq-listed biotechnology company, ContraFect Corporation. Previously, Mr Muntner served as Managing Director and Co-Head of Healthcare Investment Banking at Janney Montgomery Scott, and spent nine years at Oppenheimer & Co. and its U.S. predecessor, CIBC World Markets. He also served as an investment banker at Prudential Securities. Mr Muntner has a BFA from Carnegie Mellon and a MBA from the Anderson School at UCLA.

Fred Grossman, DO, FAPA

Chief Medical Officer

Dr Grossman has over 20 years of industry experience, and has held key leadership positions at major global pharmaceutical companies, including Eli Lilly, Johnson & Johnson (J&J), Bristol Myers Squibb (BMS), Sunovion, and Glenmark. During his career, he has managed global clinical development, pharmacovigilance, medical affairs and clinical operations for innovative product development, as well as United States Food and Drug Administration (FDA) approvals and post-market support for numerous blockbuster, specialty and generic products. Dr Grossman has led and built teams in the United States, Europe and Japan with responsibility for global medical affairs, global clinical development, health economics & outcomes research (HEOR) and global drug safety. At J&J and Eli Lilly, he was responsible for multiple New Drug Applications (NDAs) to the FDA. At BMS, he was Global Head of the Medical Affairs organization, with focus on immunology and cardiovascular diseases. As Head of Clinical Development, Medical Affairs & Drug Safety at 6,000-person global pharma Sunovion, a subsidiary of Japan’s Sumitomo Dainippon Pharma Co., Dr Grossman had responsibility across teams in the United States, Europe and Japan and successfully launched a blockbuster product in the United States market. More recently, he was CMO at Glenmark, an India-based global pharma with 12,000 people, where he oversaw a portfolio spanning biologics, branded drugs, and generics, including in immunology and immuno-oncology.

Roger D. Brown, BA

Spinal Orthopedic Disorders

Prior to joining Mesoblast in 2009, Mr Brown served as the Divisional Vice President, Clinical, Regulatory and Quality for Abbott Laboratories’ Spine Division. He has over 20 years of regulatory, clinical, product development, quality and reimbursement experience dealing with a variety of technologies from physiological monitoring equipment to implantable and biological products. Mr Brown has also held clinical and regulatory roles at Axiomed Spine Corporation, Wright Medical Technology, CryoLife and Nellcor Puritan Bennett. He received a Bachelor of Arts from Missouri’s William Jewell College and completed coursework at Oxford University in England.

Peter Howard, BSc, LLB (Hons)

Corporate Executive & General Counsel

Mr Howard has been integrally involved with Mesoblast since its inception in 2004, when he played a critical role in the corporate structuring and listing of Mesoblast on the ASX. More generally, he has extensive experience with many biopharmaceutical firms and major research institutions, covering public listings, private financings, strategic, licensing, intellectual property and mergers and acquisition activities. Mr Howard has done so in several roles, including as a partner at a major law firm, entrepreneur, director and senior executive. 

John McMannis, PhD

Manufacturing

Dr McMannis has 27 years of experience in clinical cellular therapy trials in both academic and commercial environments. Before joining Mesoblast in 2011, he served at the University of Texas MD Anderson Cancer Center as a Professor of Medicine from 1999 to 2011, and as the Director of the Cell Therapy Laboratory from 1999 to 2011, and as the Technical Director of the Cord Blood Bank from 2008 to 2011. Before his tenure at the University of Texas MD Anderson Cancer Center, Dr McMannis was a Senior Director Technical Affairs at the Immunotherapy Division of Baxter and Therapy Scientist at COBE BCT (now Terumo BCT). He has served on the scientific advisory boards at BioSafe SA, Biolife Solutions, Inc., and General Electric and on the board of directors for the American Association of Blood Banks, or AABB, and the National Marrow Donor Program, or NMDP, which operates the “Be the Match” donor program.

Julie Meldrum, Inv Rel (AIRA)

Global Corporate Communications

Ms Meldrum joined Mesoblast in 2004. She has deep and diverse experience as a corporate communications strategist, European foreign correspondent, political and business reporter and television and radio producer. Ms Meldrum also served as a senior diplomat for 14 years promoting Australian policies and industries in the key markets of Japan, Hong Kong and Indonesia and has advised Prime Ministers, Cabinet Ministers and business leaders. She has been the recipient of the League of American Communication Professionals Gold Magellan Award, the United Nations Media Peace Prize for Radio, was a Governor of the Foreign Correspondents’ Club in Hong Kong and a Director of Australian Doctors International. Ms Meldrum is senior advisor to the Washington DC-based Alliance for Regenerative Medicine’s Communications and Education Committee. 

Michael Schuster, MS, MBA

Pharma Partnering

Mr Schuster, who joined Mesoblast in 2004, leads the Company's partnering discussions. Previously he was the head of the Company's investor relations outreach program and was part of the founding executive team at both Mesoblast Limited and Angioblast Systems, Inc. Mr Schuster was Executive Vice President of Global Therapeutic Programs from 2010 to 2013 and was the Director of Business Development and Vice President of Operations from 2004 to 2010. He holds an undergraduate degree in science from Tufts University, a Master's degree in Immunology & Microbiology from New York Medical College, and a MBA from Fordham University in New York.

Karen Segal, PhD

Medical Affairs

Dr Segal has more than 20 years’ experience in the biopharmaceutical industry serving in leadership roles in global medical affairs and clinical development at Sanofi, Hoffmann LaRoche, and Mesoblast where she was therapeutic head of diabetes and metabolic diseases from 2011 to 2016. Prior to working in the biopharmaceutical industry, she held faculty appointments at Columbia University's College of Physicians and Surgeons, Mount Sinai School of Medicine, and Weill Cornell Medical College conducting United States National Institutes of Health-funded research in diabetes, metabolism and obesity and directing the exercise physiology service in pediatric cardiology. Most recently, Dr Segal was a vice president at Roivant Sciences and the metabolic disease subsidiary Metavant Sciences. 

Paul Simmons, PhD

Research & New Product Development

Prior to joining Mesoblast in 2011, Dr Simmons had nearly 30 years of experience in stem cell research, especially research in basic hematopoiesis and in precursor cells for the stromal system of the bone marrow. He served as President of the International Society of Stem Cell Research from 2006 to 2007. Dr Simmons held the C. Harold and Lorine G. Wallace Distinguished University Chair at the University of Texas Health from 2008 to 2011 and served as the inaugural Professor and Director of the Centre for Stem Cell Research at the Brown Foundation Institute of Molecular Medicine from 2006 to 2011. He is, or has served as, an associate editor, a member of the editorial board, or a reviewer on multiple scientific and medical journals including Experimental Hematology, Cytotherapy and Stem Cell Research, Cell Stem Cell, Stem Reports, Science and Nature

Donna Skerrett, MD, MS

Adviser, Graft Versus Host Disease

Dr Skerrett has more than 20 years of combined experience in transfusion medicine, cellular therapy, and transplantation. She was Director of Transfusion Medicine and Cellular Therapy at Weill Cornell Medical Center in New York from 2004 to 2011, and previously served as Associate Director of Transfusion Medicine and Director of Stem Cell Facilities at Columbia University’s New York-Presbyterian Hospital. From 2004, she held various roles at Mesoblast in clinical and regulatory affairs and was Chief Medical Officer from 2011 to 2019.

Geraldine Storton, BSc, MMS, MBA

Head of Regulatory Affairs & Quality Management

Ms Storton is a seasoned pharmaceutical executive with more than 24 years’ experience across the full value chain of Pharmaceutical and Medical Device Research and Development, production and commercialization worldwide. She has an extensive background in regulatory affairs and quality, most recently as a consultant to cell therapy companies. Prior to this, Ms Storton held executive roles at Hospira, and its predecessor companies in both regulatory affairs and quality, with a focus on major program management. As Vice President, Program Management, Quality, at Hospira headquarters in Chicago, she led a company-wide quality remediation program to improve compliance in manufacturing across 15 facilities worldwide. As Regional Director, Commercial Quality ANZ, Asia and Japan, Ms Storton was responsible for quality oversight and management of all products sold in Asia Pacific countries. Her responsibilities included regulatory compliance, batch release, field actions, complaints management, change control, due diligence and new product launch. As director of global regulatory operations, Ms Storton managed development and registration of new products and on-market management of the existing product portfolio for all Hospira’s products developed or manufactured within Asia Pacific for global distribution. She joined Mesoblast in December 2015.

Eric Strati, Pharm.D., MBA

Commercial

Eric Strati has over 17 years of experience across a broad range of industries within the healthcare sector including pharmaceutical, biotechnology, investment banking, and pharmacy benefit management. Prior to joining Mesoblast in 2015, Dr Strati held various commercial leadership roles including new product planning, lifecycle management, sales, marketing, and payer strategy. Previous positions include most recently as Executive Director, Managed Markets at Novartis, medical affairs positions at Genzyme and Bristol-Myers Squibb, and Vice President of Global Pharmaceutical Equity Research at HSBC. He earned his Bachelors of Science in Pharmacy and MBA in Health Systems Management from Union University, and Doctor of Pharmacy from University of Kansas.

Jonathan R. Symonds, CBE, BA, FCA

Corporate Finance & Strategy

Mr Symonds, who was Chief Financial Officer of Novartis AG from 2009 to 2013, became an advisor to Mesoblast in 2014. Prior to joining Novartis, Mr Symonds was a Partner and Managing Director of Goldman Sachs Group Inc (2007-2009), Chief Financial Officer of AstraZeneca plc (1997-2007) and a Partner of KPMG (1992-1997). In 2014, he was appointed an independent non-executive Director of HSBC Holdings plc and Chairman of HSBC’s European subsidiary, HSBC Bank plc. He is a non-executive Director of Genomics England Limited. Previous roles include non-executive Director of Diageo plc and Qinetiq plc., Chairman of the 100 Group of Finance Directors, Joint Chairman of the Business Tax Forum, board member of the Accounting Standards Board, and founder of the Oxford University Centre for Business Taxation Research, all in the United Kingdom. In 2007, Mr Symonds was awarded a Commander of the British Empire for service to industry.