Silviu Itescu - MBBS, FRACP, FACP, FTSE
Chief Executive Officer and Managing Director
Prior to founding Mesoblast in 2004, Professor Silviu Itescu established an outstanding international reputation as a physician scientist in the fields of stem cell biology, autoimmune diseases, organ transplantation, and heart failure. He is an active faculty member of Melbourne and Monash universities in Australia and was previously a faculty member of Columbia University in New York. Under his leadership, Mesoblast received the 2011 Deals of Distinction™ Award from The Licensing Executives Society (United States and Canada) Inc. for its alliance with Cephalon, Inc., later acquired by Teva Pharmaceutical Industries Ltd, and the 2013 Scrip Award for Financing Deal of the Year. In 2011, Professor Itescu was named BioSpectrum Asia Person of the Year. In 2013 he received the inaugural Key Innovator Award from the Vatican's Pontifical Council for Culture for his leadership and ingenuity in translational science and clinical medicine in relation to adult stem cell therapy. Professor Itescu has consulted for various international pharmaceutical companies, has been an adviser to biotechnology and health care investor groups, and has served on the Board of Directors of a number of publicly-listed life sciences companies.
Roger D. Brown - BA
Spine and Musculoskeletal Diseases
Prior to joining Mesoblast, Roger Brown served as the Divisional Vice President, Clinical, Regulatory and Quality for Abbott Laboratories’ Spine Division. He has over 20 years of regulatory, clinical, product development, quality and reimbursement experience dealing with a variety of technologies from physiological monitoring equipment to implantable and biological products. Mr Brown has also held clinical and regulatory roles at Axiomed Spine Corporation, Wright Medical Technology, CryoLife and Nellcor Puritan Bennett. He received a Bachelor of Arts from Missouri’s William Jewell College and completed coursework at Oxford University in England.
Lee Golden - MD
Dr Lee Golden, MD, is a trained interventional cardiologist with over 20 years of clinical and industry experience. He started his industry career at Pfizer as a Medical Director on the global Lipitor team, where his responsibilities included overseeing multinational cardiovascular trials. Dr Golden has extensive experience across several therapeutic areas, with orphan diseases, and with global drug development of both small molecules and biologics. Prior to joining Mesoblast, he was the Global Therapeutic Head for Cardiovascular and Hematology at Eisai where he managed multiple development programs from preclinical through to commercialization.
Peter Howard - BSc, LLB (Hons)
General Counsel and Corporate Executive
Peter Howard joined Mesoblast in July 2011. Prior to that he initiated and managed a leading Australian law firm’s biotechnology and life sciences legal practice with a focus on international assets and fundraising on the Australian Securities Exchange (ASX). Mr Howard’s role encompassed intellectual property asset management, strategy, licensing, mergers and acquisitions and capital raising. He has extensive experience in the Australian biotechnology industry, including as a director of private companies and working in Europe and at Australian research institutes to commercialize their technologies.
Judith R. Jaeger - MD
Dr Judith R. Jaeger, MD, is board-certified in both internal medicine and pulmonary disease. Prior to joining Mesoblast in 2011, she had extensive experience in clinical pharmaceutical development which included development of oral, inhaled and injectable therapies, small molecules and monoclonal antibodies, which spanned translational medicine through to Phase 4 clinical trials. Dr Jaeger worked at Boehringer Ingelheim, Roche, and various biotechnology companies in the fields of inflammation and immunology, including rheumatoid arthritis, respiratory diseases, and ischemic stroke.
Sue MacLeman – BPharm, MMktg, MLaw, FACPP, FAICD
Sue MacLeman worked initially in hospital pharmacy roles before moving to the pharmaceuticals industry and working in various development and commercialization roles with Merck, Amgen and Bristol-Myers Squibb. She has also been CEO and Board member of a number of publicly-listed companies in both the United States and Australia. Mrs MacLeman is a member of the Pharmaceutical Industry Council and the Australian Government Pharmaceutical Industry Working Group. In 2011 she was appointed to the Victorian Biotechnology Advisory Council.
John D. McMannis - PhD
For the past 25 years, John McMannis has been involved in clinical cellular therapy trials in both academic and commercial environments and is considered an expert in translational research and large scale manufacturing. Before joining Mesoblast, he spent 13 years at the University of Texas MD Anderson Cancer Center as a Professor of Medicine, the Director of the Cell Therapy Laboratory and the Technical Director of the Cord Blood Bank. Prior to this, Dr McMannis was at the Immunotherapy Division of Baxter and COBE BCT (now Terumo BCT). He has served on a number of Scientific Advisory Boards and Board of Directors for commercial entities and organizations in the cellular field.
Julie Meldrum - Inv Rel (AIRA)
Global Corporate Communications
Julie Meldrum has deep and diverse experience as a corporate communications strategist, European foreign correspondent, political and business reporter and television and radio producer. She also served as a senior diplomat for 14 years promoting Australian policies and industries in the key markets of Japan, Hong Kong and Indonesia and has advised Prime Ministers, Cabinet Ministers and business leaders. Ms Meldrum has been the recipient of the League of American Communication Professionals Gold Magellan Award, the United Nations Media Peace Prize for Radio, was a Governor of the Foreign Correspondents’ Club in Hong Kong and a Director of Australian Doctors International. She is co-chair of the Washington DC-based Alliance of Regenerative Medicine’s Communications and Education Committee. Ms Meldrum joined Mesoblast in 2004.
Kenneth Newman, MD, MBA
Global Clinical Development
Dr Kenneth Newman, MD, is a pulmonologist with extensive pharmaceutical experience, including guiding products through all phases of clinical development. He has been an executive at both large and small pharmaceutical companies including Boehringer Ingelheim, Forest Laboratories and most recently Acton Pharmaceuticals. He has conducted a large number of late-stage clinical trial programs, submitted numerous successful NDAs, and had products approved in the United States and other markets. Dr Newman has worked across multiple therapeutic areas including metabolic, cardiovascular, pain, neurology, oncology, respiratory, urology and women’s health.
Jenni Pilcher - CA, BBS
Chief Financial Officer and Company Secretary
Since qualifying as a Chartered Accountant with Price Waterhouse, Jenni Pilcher has worked in corporate and business financial roles for high profile international companies in pharmaceuticals, FMCG (fast moving consumer goods) and services. Before joining Mesoblast as Financial Controller in 2007, she spent six years with ASX 200 Company, Spotless Group, progressing through a variety of financial roles. Previously Mrs Pilcher worked in the finance teams at Cadbury Schweppes plc and international pharmaceutical group Medeva plc, both based in the United Kingdom. She was appointed Chief Financial Officer of Mesoblast in November 2007 and Company Secretary in January 2012.
Michael Schuster – MS, BSc, MBA
New Product and Technology Evaluation, Investor Relations
Michael Schuster was a founding executive at Mesoblast prior to its public listing in 2004. He has led Mesoblast's product operational activities, and has been a member of the corporate executive leadership team developing the Company's strategic, technical, and commercial plans. Mr Schuster also leads Mesoblast’s investor relations outreach program. He holds an undergraduate degree in science from Tufts University, a Master's degree in Immunology & Microbiology from New York Medical College, and a Masters of Business Administration from Fordham University in New York.
Karen Segal - PhD
Diabetes and Metabolic Diseases
Karen Segal established herself as a senior academic investigator for more than 15 years in diabetes, metabolism and obesity at Columbia University's College of Physicians and Surgeons, Mount Sinai School of Medicine, and Weill Cornell Medical College. Prior to joining Mesoblast, she worked for 15 years in leadership roles at Hoffmann La Roche and at Sanofi-Aventis in global clinical development and medical affairs for programs in diabetes and metabolism.
Paul J. Simmons - BSc, PhD
Research and New Product Development
Professor Paul Simmons has had a long and distinguished career in stem cell research and his contributions to the field were recognized by his election as President of the International Society of Stem Cell Research from 2006 to 2007. He has received international recognition for his pioneering contributions to basic hematopoiesis research and of precursor cells for the stromal system of the bone marrow. Professor Simmons has been an editor and reviewer for multiple international journals and is a member of F1000. Prior to joining Mesoblast, he held the C. Harold and Lorine G. Wallace Distinguished University Chair at the University of Texas Health and was appointed as the inaugural Professor and Director of the Centre for Stem Cell Research at the Brown Foundation Institute of Molecular Medicine.
Donna Skerrett - MD, MS
Chief Medical Officer
Dr Donna Skerrett, MD, has been involved in stem cell procurement, manipulation and transplantation for nearly 20 years and her areas of expertise include conventional transfusion medicine, immunohematology, apheresis, histocompatibility testing and stem cell apheresis and processing; and novel regenerative medicine translational therapy. She has worked on the design and execution of conventional and novel stem cell therapies in hematopoietic recovery, cardiac repair, skeletal repair, cartilage preservation, angiogenesis stabilization in eye disease and most recently inflammatory and metabolic diseases. Dr Skerrett was Director of the Stem Cell Facilities at Weill-Cornell Medical Center in New York, and previously served as Associate Director of Transfusion Medicine at Columbia University's New York-Presbyterian Hospital. She is an advisor to the New York State Department of Health on the Progenitor Cell Committee and has been Chair of the Governor's Council on Blood and Transfusion Services. Dr Skerrett joined Mesoblast in 2004.
Darin Weber - PhD
Global Regulatory Affairs
Darin Weber is a leading regulatory expert for cellular and tissue-based regenerative medicine products. Prior to joining Mesoblast, he worked as a senior consultant at Biologics Consulting Group, Inc., working with a number of leading regenerative medicine academic and industry firms, specializing in stem cell based therapies and combination products. Dr Weber is an active participant in key stakeholder organizations, serving on the United States Pharmacopeia Expert Committee responsible for cellular and tissue-based products as well as committees within the International Society for Cellular Therapy and the American Association of Blood Banks, among others. Prior to becoming a consultant, he spent over seven years at the United States Food and Drug Administration (FDA) Center for Biologics Evaluation and Research, working as a regulatory project manager, regulatory review officer and most notably as Chief, Cellular Therapy Branch in the then newly-created Office of Cellular, Tissue and Gene Therapies. During his time at the FDA, Dr Weber was actively involved in the development of policies and guidance documents for cellular and tissue-based products.